Selected studies include (but are not limited to) efforts to 1) test the ability of lunar regolith to act as a growth substrate for crop-producing plants including grains, tomatoes and potatoes, 2) understand how growth in lunar regolith influences plant and microbial interactions, and how in turn, these interactions affect plant development and health, 3) identify and test bioremediation methods/techniques to enhance the ability of regolith to act as a growth substrate, and 4) understand how lunar dust exposure impacts host/microbial interactions in human-analogous model systems under simulated microgravity conditions.